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1

WDR5 Associates with Histone H3 Methylated at K4 and Is Essential for H3 K4 Methylation and Vertebrate Development

Joanna Wysocka, Tomek Swigut, Thomas A. Milne, Yali Dou, Xin Zhang, Alma L. Burlingame, Robert G. Roeder, Ali H. Brivanlou, C. David Allis

Journal:

Year:

2005

Language:

english

File:

PDF, 899 KB

english, 2005

2

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

Peng, Dongjun, Kryczek, Ilona, Nagarsheth, Nisha, Zhao, Lili, Wei, Shuang, Wang, Weimin, Sun, Yuqing, Zhao, Ende, Vatan, Linda, Szeliga, Wojciech, Kotarski, Jan, Tarkowski, Rafał, Dou, Yali, Cho, Kath

Journal:

Year:

2015

Language:

english

File:

PDF, 11.05 MB

english, 2015

3

MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency

Zhang, Hui, Gayen, Srimonta, Xiong, Jie, Zhou, Bo, Shanmugam, Avinash K., Sun, Yuqing, Karatas, Hacer, Liu, Liu, Rao, Rajesh C., Wang, Shaomeng, Nesvizhskii, Alexey I., Kalantry, Sundeep, Dou, Yali

Journal:

Year:

2016

Language:

english

File:

PDF, 4.99 MB

english, 2016

4

NSUN2-mediated m5C Methylation and METTL3/METTL14-mediated m6A Methylation Cooperatively Enhance p21 Translation

Li, Qiu, Li, Xiu, Tang, Hao, Jiang, Bin, Dou, Yali, Gorospe, Myriam, Wang, Wengong

Journal:

Journal of Cellular Biochemistry

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

5

HuR regulates phospholamban expression in isoproterenol-induced cardiac remodeling

Hu, Han, Jiang, Mingyang, Cao, Yangpo, Zhang, Zhuojun, Jiang, Bin, Tian, Feng, Feng, Juan, Dou, Yali, Gorospe, Myriam, Zheng, Ming, Zheng, Lemin, Yang, Zhongzhou, Wang, Wengong

Journal:

Cardiovascular Research

Year:

2019

Language:

english

File:

PDF, 1.65 MB

english, 2019

6

Developmental ROS individualizes organismal stress resistance and lifespan

Bazopoulou, Daphne, Knoefler, Daniela, Zheng, Yongxin, Ulrich, Kathrin, Oleson, Bryndon J., Xie, Lihan, Kim, Minwook, Kaufmann, Anke, Lee, Young-Tae, Dou, Yali, Chen, Yong, Quan, Shu, Jakob, Ursula

Journal:

Year:

2019

File:

PDF, 10.54 MB

2019

7

p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

Li, Qiang, Mao, Fengbiao, Zhou, Bo, Huang, Yuanhao, Zou, Zhenhua, denDekker, Aaron D., Xu, Jing, Hou, Sean, Liu, Jie, Dou, Yali, Rao, Rajesh C.

Journal:

Year:

2020

Language:

english

File:

PDF, 6.56 MB

english, 2020

8

Publisher Correction: Cryo-EM structure of the human MLL1 core complex bound to the nucleosome

Park, Sang Ho, Ayoub, Alex, Lee, Young-Tae, Xu, Jing, Kim, Hanseong, Zheng, Wei, Zhang, Biao, Sha, Liang, An, Sojin, Zhang, Yang, Cianfrocco, Michael A., Su, Min, Dou, Yali, Cho, Uhn-Soo

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 380 KB

english, 2020

9

Global observation of urban expansion and land-cover dynamics using satellite big-data

Kuang, Wenhui, Du, Guoming, Lu, Dengsheng, Dou, Yinyin, Li, Xiaoyong, Zhang, Shu, Chi, Wenfeng, Dong, Jinwei, Chen, Guangsheng, Yin, Zherui, Pan, Tao, Hamdi, Rafiq, Hou, Yali, Chen, Chunyang, Li, Han,

Journal:

Science Bulletin

Year:

2020

File:

PDF, 3.09 MB

2020

10

Impaired CD4+ T-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis

William F. Carson, Karen A. Cavassani, Toshihiro Ito, Matthew Schaller, Makoto Ishii, Yali Dou, Steven L. Kunkel

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 399 KB

english, 2010

11

Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia

Yali Dou, Jay L. Hess

Journal:

International Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 302 KB

english, 2008

12

Regulation of MLL1 H3K4 methyltransferase activity by its core components

Dou, Yali, Milne, Thomas A, Ruthenburg, Alexander J, Lee, Seunghee, Lee, Jae Woon, Verdine, Gregory L, Allis, C David, Roeder, Robert G

Journal:

Nature Structural and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 249 KB

english, 2006

13

Physical Association and Coordinate Function of the H3 K4 Methyltransferase MLL1 and the H4 K16 Acetyltransferase MOF

Yali Dou, Thomas A. Milne, Alan J. Tackett, Edwin R. Smith, Aya Fukuda, Joanna Wysocka, C. David Allis, Brian T. Chait, Jay L. Hess, Robert G. Roeder

Journal:

Year:

2005

Language:

english

File:

PDF, 703 KB

english, 2005

14

Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions

Alexander J. Ruthenburg, Haitao Li, Thomas A. Milne, Scott Dewell, Robert K. McGinty, Melanie Yuen, Beatrix Ueberheide, Yali Dou, Tom W. Muir, Dinshaw J. Patel, C. David Allis

Journal:

Year:

2011

Language:

english

File:

PDF, 1.95 MB

english, 2011

15

Two Mammalian MOF Complexes Regulate Transcription Activation by Distinct Mechanisms

Xiangzhi Li, Lipeng Wu, Callie Ann Sprunger Corsa, Steve Kunkel, Yali Dou

Journal:

Year:

2009

Language:

english

File:

PDF, 1.11 MB

english, 2009

16

The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation

Lipeng Wu, Barry M. Zee, Yanming Wang, Benjamin A. Garcia, Yali Dou

Journal:

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

17

FOXP3 Orchestrates H4K16 Acetylation and H3K4 Trimethylation for Activation of Multiple Genes by Recruiting MOF and Causing Displacement of PLU-1

Hiroto Katoh, Zhaohui S. Qin, Runhua Liu, Lizhong Wang, Weiquan Li, Xiangzhi Li, Lipeng Wu, Zhanwen Du, Robert Lyons, Chang-Gong Liu, Xiuping Liu, Yali Dou, Pan Zheng, Yang Liu

Journal:

Year:

2011

Language:

english

File:

PDF, 2.47 MB

english, 2011

18

The Histone Acetyltransferase MOF Is a Key Regulator of the Embryonic Stem Cell Core Transcriptional Network

Xiangzhi Li, Li Li, Ruchi Pandey, Jung S. Byun, Kevin Gardner, Zhaohui Qin, Yali Dou

Journal:

Year:

2012

Language:

english

File:

PDF, 1.80 MB

english, 2012

19

Phosphorylation of Linker Histone H1 Regulates Gene Expression In Vivo by Creating a Charge Patch

Yali Dou, Martin A. Gorovsky

Journal:

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

20

Phosphorylation of Linker Histone H1 Regulates Gene Expression In Vivo by Mimicking H1 Removal

Yali Dou, Craig A Mizzen, Marc Abrams, C.David Allis, Martin A Gorovsky

Journal:

Year:

1999

Language:

english

File:

PDF, 151 KB

english, 1999

21

High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction

Karatas, Hacer, Townsend, Elizabeth C., Cao, Fang, Chen, Yong, Bernard, Denzil, Liu, Liu, Lei, Ming, Dou, Yali, Wang, Shaomeng

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 786 KB

english, 2013

22

ASH2L Regulates Ubiquitylation Signaling to MLL: trans-Regulation of H3 K4 Methylation in Higher Eukaryotes

Wu, Lipeng, Lee, Shirley Y., Zhou, Bo, Nguyen, Uyen T.T., Muir, Tom W., Tan, Song, Dou, Yali

Journal:

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

23

Regulation of transcription by the MLL2 complex and MLL complex–associated AKAP95

Jiang, Hao, Lu, Xiangdong, Shimada, Miho, Dou, Yali, Tang, Zhanyun, Roeder, Robert G

Journal:

Nature Structural and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

24

IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L

Kryczek, Ilona, Lin, Yanwei, Nagarsheth, Nisha, Peng, Dongjun, Zhao, Lili, Zhao, Ende, Vatan, Linda, Szeliga, Wojciech, Dou, Yali, Owens, Scott, Zgodzinski, Witold, Majewski, Marek, Wallner, Grzegorz,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.46 MB

english, 2014

25

H2B Ubiquitylation Promotes RNA Pol II Processivity via PAF1 and pTEFb

Wu, Lipeng, Li, Li, Zhou, Bo, Qin, Zhaohui, Dou, Yali

Journal:

Year:

2014

Language:

english

File:

PDF, 2.43 MB

english, 2014

26

H2A.Z Sets the Stage in ESCs

Pandey, Ruchi, Dou, Yali

Journal:

Year:

2013

Language:

english

File:

PDF, 160 KB

english, 2013

27

Analysis of the Binding of Mixed Lineage Leukemia 1 (MLL1) and Histone 3 Peptides to WD Repeat Domain 5 (WDR5) for the Design of Inhibitors of the MLL1−WDR5 Interaction

Karatas, Hacer, Townsend, Elizabeth C., Bernard, Denzil, Dou, Yali, Wang, Shaomeng

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.24 MB

english, 2010

28

let-7-repressesed Shc translation delays replicative senescence

Xu, Fang, Pang, Lijun, Cai, Xiaoyu, Liu, Xinwen, Yuan, Shuai, Fan, Xiuqin, Jiang, Bin, Zhang, Xiaowei, Dou, Yali, Gorospe, Myriam, Wang, Wengong

Journal:

Year:

2014

Language:

english

File:

PDF, 680 KB

english, 2014

29

Epigenetic regulation of immune cell functions during post-septic immunosuppression

Carson, William F., Cavassani, Karen A., Dou, Yali, Kunkel, Steven L.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.28 MB

english, 2011

30

Structure-based design of conformationally constrained cyclic peptidomimetics to target the MLL1-WDR5 protein–protein interaction as inhibitors of the MLL1 methyltransferase activity

Karatas, Hacer, Lee, Shirley Y., Townsend, Elizabeth C., Cao, Fang, Xu, Jing, Bernard, Denzil, Liu, Liu, Dou, Yali, Wang, Shaomeng

Journal:

Chinese Chemical Letters

Year:

2015

Language:

english

File:

PDF, 767 KB

english, 2015

31

One-pot refolding of core histones from bacterial inclusion bodies allows rapid reconstitution of histone octamer

Lee, Young-Tae, Gibbons, Garrett, Lee, Shirley Y., Nikolovska-Coleska, Zaneta, Dou, Yali

Journal:

Protein Expression and Purification

Year:

2015

Language:

english

File:

PDF, 992 KB

english, 2015

32

New perspectives for the regulation of acetyltransferase MOF

Li, Xiangzhi, Dou, Yali

Journal:

Year:

2010

Language:

english

File:

PDF, 295 KB

english, 2010

33

Hijacked in cancer: the KMT2 (MLL) family of methyltransferases

Rao, Rajesh C., Dou, Yali

Journal:

Nature Reviews Cancer

Year:

2015

Language:

english

File:

PDF, 703 KB

english, 2015

34

Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma

Khan, Mehnaz, Walters, Laura L, Li, Qiang, Thomas, Dafydd G, Miller, Jason M L, Zhang, Qitao, Sciallis, Andrew P, Liu, Yu, Dlouhy, Brian J, Fort, Patrice E, Archer, Steven M, Demirci, Hakan, Dou, Yali

Journal:

Laboratory Investigation

Year:

2015

Language:

english

File:

PDF, 6.08 MB

english, 2015

35

Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30

Chen, Yong, Cao, Fang, Wan, Bingbing, Dou, Yali, Lei, Ming

Journal:

Year:

2012

File:

PDF, 510 KB

2012

36

Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30

Chen, Yong, Cao, Fang, Wan, Bingbing, Dou, Yali, Lei, Ming

Journal:

Year:

2012

Language:

english

File:

PDF, 510 KB

english, 2012

37

Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex

Huang, Jing, Wan, Bingbing, Wu, Lipeng, Yang, Yuting, Dou, Yali, Lei, Ming

Journal:

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

38

Phosphorylation and an ATP-Dependent Process Increase the Dynamic Exchange of H1 in Chromatin

Yali Dou, Josephine Bowen, Yifan Liu and Martin A. Gorovsky

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 2.36 MB

english, 2002

39

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding

Chen, Yong, Wan, Bingbing, Wang, Kevin C, Cao, Fang, Yang, Yuting, Protacio, Angeline, Dou, Yali, Chang, Howard Y, Lei, Ming

Journal:

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

40

PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity

Zhou, Bo, Wang, Jingya, Lee, Shirley Y., Xiong, Jie, Bhanu, Natarajan, Guo, Qi, Ma, Peilin, Sun, Yuqing, Rao, Rajesh C., Garcia, Benjamin A., Hess, Jay L., Dou, Yali

Journal:

Year:

2016

Language:

english

File:

PDF, 5.09 MB

english, 2016

41

MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition

Luo, Huacheng, Shenoy, Anitha K., Li, Xuehui, Jin, Yue, Jin, Lihua, Cai, Qingsong, Tang, Ming, Liu, Yang, Chen, Hao, Reisman, David, Wu, Lizi, Seto, Edward, Qiu, Yi, Dou, Yali, Casero, Robert A., Lu,

Journal:

Year:

2016

Language:

english

File:

PDF, 4.84 MB

english, 2016

42

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] A20. EMERGING APPROACHES TO RESPIRATORY INFECTIONS: LATE BREAKING ABSTRACTS - Mice Haploinsufficient For The Histone Methyltransferase MLL Exhibit Decreased Inflammatory Responses During Polymicrobial Sepsis

Carson IV, William F., Cavassani, Karen, Schaller, Matthew, Li, Xiangzhi, Ishii, Makoto, Ito, Toshihiro, Lukacs, Nicholas W., Hogaboam, Cory M., Dou, Yali, Kunkel, Steven

Year:

2011

Language:

english

File:

PDF, 18 KB

english, 2011

43

Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts

Liu, Liu, Lei, Ienglam, Karatas, Hacer, Li, Yangbing, Wang, Li, Gnatovskiy, Leonid, Dou, Yali, Wang, Shaomeng, Qian, Li, Wang, Zhong

Journal:

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

44

MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program

Xu, Jing, Li, Li, Xiong, Jie, denDekker, Aaron, Ye, Andrew, Karatas, Hacer, Liu, Liu, Wang, He, Qin, Zhaohui S, Wang, Shaomeng, Dou, Yali

Journal:

Year:

2016

Language:

english

File:

PDF, 2.10 MB

english, 2016

45

Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer

Bai, Longchuan, Zhou, Bing, Yang, Chao-Yie, Ji, Jiao, McEachern, Donna, Przybranowski, Sally, Jiang, Hui, Hu, Jiantao, Xu, Fuming, Zhao, Yujun, Liu, Liu, Fernandez-Salas, Ester, Xu, Jing, Dou, Yali, W

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

46

Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia

Albert, Lea, Xu, Jing, Wan, Ruiwei, Srinivasan, Vasundara, Dou, Yali, Vazquez, Olalla

Journal:

Chemical Science

Year:

2017

Language:

english

File:

PDF, 1.59 MB

english, 2017

47

EpiDenovo: a platform for linking regulatory de novo mutations to developmental epigenetics and diseases

Mao, Fengbiao, Liu, Qi, Zhao, Xiaolu, Yang, Haonan, Guo, Sen, Xiao, Luoyuan, Li, Xianfeng, Teng, Huajing, Sun, Zhongsheng, Dou, Yali

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 3.37 MB

english, 2017

48

Phosphoproteomics links glycogen synthase kinase-3 to RNA splicing

Khoa, Le Tran Phuc, Dou, Yali

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 234 KB

english, 2017

49

Maternal and neonatal outcomes of placenta increta and percreta from a multicenter study in China

Zhang, Huijing, Dou, Ruochong, Yang, Huixia, Zhao, Xianlan, Chen, Dunjin, Ding, Yilin, Ding, Hongjuan, Cui, Shihong, Zhang, Weishe, Xin, Hong, Gu, Weirong, Hu, Yali, Ding, Guifeng, Qi, Hongbo, Fan, Li

Journal:

Journal of Maternal-Fetal and Neonatal Medicine

Year:

2018

Language:

english

File:

PDF, 828 KB

english, 2018

50

Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis

Zhang, Heng, Zhou, Bo, Qin, Su, Xu, Jing, Harding, Rachel, Tempel, Wolfram, Nayak, Vinod, Li, Yanjun, Loppnau, Peter, Dou, Yali, Min, Jinrong

Journal:

Genes & Development

Year:

2018

Language:

english

File:

PDF, 5.37 MB

english, 2018